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- Vapaliximab-iFluor 546
Vapaliximab-iFluor 546 (CAT#: ADC-FL-059)
This product is comprised of an anti-AOC3 monoclonal antibody (Vapaliximab) labeled with iFluor 546. iFluor 546 is a yellow-fluorescent dye and it's excitation/emission is 556/573 nm.
- TARGET
- ANTIBODY
- DYE
- Name
- AOC3
- Alternative Names
- AOC3; amine oxidase, copper containing 3 (vascular adhesion protein 1); membrane primary amine oxidase; HPAO; VAP 1; VAP1; copper amine oxidase; vascular adhesion protein 1; semicarbazide-sensitive amine oxidase; SSAO; VAP-1;
- Overview
- This gene encodes a member of the semicarbazide-sensitive amine oxidase family. Copper amine oxidases catalyze the oxidative conversion of amines to aldehydes in the presence of copper and quinone cofactor. The encoded protein is localized to the cell surface, has adhesive properties as well as monoamine oxidase activity, and may be involved in leukocyte trafficking. Alterations in levels of the encoded protein may be associated with many diseases, including diabetes mellitus. A pseudogene of this gene has been described and is located approximately 9-kb downstream on the same chromosome. Alternative splicing results in multiple transcript variants.
- Overview
- Chimeric Anti-AOC3 IgG2 antibody, Vapaliximab
- Generic name
- Vapaliximab
- Species Reactivity
- Human
- Name
- iFluor 546
- Color
- Yellow
- Excitation⁄Emission (nm)
- 556/573
- Detection method
- Fluorescent
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Other Products
Same Target
| CAT# | Product Name | Linker | Payload |
| ADC-W-679 | Anti-AOC3 (Vepalimomab)-MC-Vc-PAB-DMEA-(PEG2)-duocarmycin SA ADC | MC-Vc-PAB-DMEA-(PEG2) | duocarmycin SA |
| ADC-W-675 | Anti-AOC3 (Vepalimomab)-SPDB-DM4 ADC | SPDB (N-succinimidyl-4-(2-pyridyldithio)butyrate) | DM4 (N2'-Deacetyl-N2'-(4-mercapto-4-methyl-1-oxopentyl)maytansine) |
| ADC-W-671 | Anti-AOC3 (Vapaliximab)-MC-Vc-PAB-MMAE ADC | MC-Vc-PAB (maleimidocaproyl-valine-citrulline-p-aminobenzoyloxycarbonyl) | MMAE |
| ADC-W-668 | Anti-AOC3 (Vapaliximab) (Vapaliximab)-SMCC-DM1 ADC | SMCC (N-succinimidyl 4-(Nmaleimidomethyl)cyclohexane-1-carboxylate) | DM1 (N2'-Deacetyl-N2'-(3-mercapto-1-oxopropyl)maytansine) |
| ADC-W-669 | Anti-AOC3 (Vapaliximab)-SPDB-DM4 ADC | SPDB (N-succinimidyl-4-(2-pyridyldithio)butyrate) | DM4 (N2'-Deacetyl-N2'-(4-mercapto-4-methyl-1-oxopentyl)maytansine) |
For Research Use Only. NOT FOR CLINICAL USE.
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