Visilizumab-iFluor 555 (ADC-FL-582)

This product is comprised of an anti-CD3E monoclonal antibody (Visilizumab) labeled with iFluor 555. iFluor 555 is a fluorescent dye and it's excitation/emission is 555/580 nm.

 TARGET

  • Name
  • CD3E
  • Alternative Names
  • CD3E; CD3e molecule, epsilon (CD3-TCR complex); CD3e antigen, epsilon polypeptide (TiT3 complex); T-cell surface glycoprotein CD3 epsilon chain; CD3-epsilon; T-cell surface antigen T3/Leu-4 epsilon chain; T-cell antigen receptor complex, epsilon subunit of T3; T3E; TCRE; FLJ18683
  • Overview
  • The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women.

 ANTIBODY

  • Overview
  • Humanized Anti-CD3E IgG2 antibody, Visilizumab
  • Generic name
  • Visilizumab
  • Species Reactivity
  • Human

 DYE

  • Name
  • iFluor 555
  • Excitation⁄Emission (nm)
  • 555/580
  • Detection method
  • Fluorescent

For Research Use Only. NOT FOR CLINICAL USE.


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