Creative Biolabs is offering the most comprehensive services for antibody development projects. With strict regulation and effective execution, we are dedicated to providing the most valuable solutions to complete your projects.
HighlightsWith over a decade of experience in phage display technology, Creative Biolabs can provide a series of antibody or peptide libraries that are available for licensing or direct screening. These ready-to-use libraries are invaluable resources for isolating target-specific binders for various research, diagnostic or therapeutic applications. Highlights
Creative Biolabs has established a broad range of platforms for developing novel antibodies or equivalents. These cutting-edge technologies enable our scientists to meet your demands from different aspects and tailor the most appropriate solution that contributes to the success of your projects.
HighlightsWith deep understanding in antibody-related realms and extensive project experience, Creative Biolabs offers a variety of references to help you learn more about our capacities and achievements, including infographic, flyer, case study, peer-reviewed publications, and all kinds of knowledge that can assist your projects. You are also welcome to contact us directly for more specific solutions.
HighlightsGet a real taste of Creative Biolabs, one of the most professional custom service providers in the world. We are committed to providing highly customized comprehensive solutions with the best quality to advance your projects.
HighlightsAdrenergic receptors are seven-transmembrane receptors, which consist of a single polypeptide chain with seven hydrophobic regions that form alpha-helical structures that span or transverse the membrane. These receptors mediate the central and peripheral actions of the neurotransmitter norepinephrine (noradrenaline) and the hormone epinephrine (adrenaline), which are catecholamine messengers that play important roles in the regulation of diverse physiological systems. The adrenergic receptors are divided into three major types: alpha-1, alpha-2, and beta. Each of these three receptors types is further divided into three subtypes. Each of these receptors couples to a distinct class of G proteins and they can also interact with other signaling proteins and pathways.
Adrenergic receptors are clinically important due to their key role in physiology, therapeutic potential as drug targets, and the contribution to different diseases. Thus, they have been actively studied for their pharmacological and molecular characteristics. Drugs which activate or inhibit adrenergic receptors have proven useful in the treatment of a variety of disorders, including nasal congestion, hypertension, glaucoma, asthma, premature labor, benign prostatic hypertrophy, and angina.
Here, we give an introduction to each subtype of adrenergic receptors, involving their structure, distribution, signaling pathways, physiologic actions, functions in disease pathology, and ligand development, etc.
Due to their importance and relevance in human physiology and pharmacology, investigators have been focusing on these receptors for different applications. To promote the research development of our clients, Creative Biolabs now provides custom-oriented services in the reconstitution of membrane proteins into various formats. Aided by our versatile Magic™ membrane protein production platform, Creative Biolabs is proud to solubilize/stabilize your target proteins in different membrane-like environments, ranging from classical detergent micelles and proteoliposomes to new emerging nanodiscs, lipoparticles, amphipols, and SMALPs. Having a group of seasoned scientists, we can help to choose an optimal format for your protein based on the required downstream applications and the biochemistry of the targets.
Specifically, our Magic™ membrane protein antibody discovery platform is able to develop highly functional anti-membrane protein antibodies against your target antigens. Creative Biolabs also presents DNA immunization service for anti-membrane protein antibody development service for anti-membrane protein antibody development. If you are interested in our services, please feel free to contact us for more information.
All listed services and products are For Research Use Only. Do Not use in any diagnostic or therapeutic applications.
