Creative Biolabs is offering the most comprehensive services for antibody development projects. With strict regulation and effective execution, we are dedicated to providing the most valuable solutions to complete your projects.
HighlightsCreative Biolabs is offering the most comprehensive services for antibody development projects. With strict regulation and effective execution, we are dedicated to providing the most valuable solutions to complete your projects.
HighlightsCreative Biolabs has established a broad range of platforms for developing novel antibodies or equivalents. These cutting-edge technologies enable our scientists to meet your demands from different aspects and tailor the most appropriate solution that contributes to the success of your projects.
HighlightsWith deep understanding in antibody-related realms and extensive project experience, Creative Biolabs offers a variety of references to help you learn more about our capacities and achievements, including infographic, flyer, case study, peer-reviewed publications, and all kinds of knowledge that can assist your projects. You are also welcome to contact us directly for more specific solutions.
HighlightsGet a real taste of Creative Biolabs, one of the most professional custom service providers in the world. We are committed to providing highly customized comprehensive solutions with the best quality to advance your projects.
HighlightsThe angiotensin II receptor family is composed of two receptors: AGTR1 and AGTR2. They belong to the G-protein-coupled receptor family and they bind angiotensin II as their ligands. Angiotensin II is a multifunctional peptide hormone and the principle effector molecule of the renin-angiotensin system (RAS) that regulates a variety of biological functions, including regulation of blood pressure, plasma volume, and cardiac, renal and neuronal functions, and thirst responses. AGTR1 mediates the classic physiological effects of Angiotensin II, such as vasoconstriction, aldosterone, and vasopressin, sodium and water retention, sympathetic facilitation, cell proliferation, etc. On the other hand, AGTR2 may exhibit opposing biological functions. This receptor is more plentiful in fetus and neonate. Studies have reported a role for AGTR2 in cardiovascular, brain, and renal function as well as in cell differentiation, tissue repair, and apoptosis.
Since angiotensin II receptors are involved in so many physiological processes and the pathophysiology of different diseases, they have been extensively studied and therapeutic interventions have also been developed. Here, we give an introduction of these two human angiotensin II receptors regarding the structure, signaling pathway, biological functions, etc.
For biochemical and biophysical characterization, it is necessary for membrane proteins to be isolated from their native amphipathic environments and introduced into an artificial environment that is expected to preserve their structural integrity and function. Creative Biolabs has developed a robust platform for the preparation of purified, stable, and functional membrane proteins, enabling detailed in vitro investigation of their structures and for further applications. Please see MemDX™ membrane protein production platform, where you can prepare your target proteins into different systems, such as detergent micelles, proteoliposomes, nanodiscs, MP-VLPs, and polymers.
Meanwhile, our MemDX™ membrane protein antibody discovery platform helps to develop antibodies against these membrane protein antigens, using unparalleled hybridoma and phage display technologies. We also present DNA immunization service for anti-membrane protein antibody development. contact us to experience the great value of our expert services.
All listed services and products are For Research Use Only. Do Not use in any diagnostic or therapeutic applications.
