Full Name
Advanced Glycosylation End-Product Specific Receptor

Keywords
Advanced Glycosylation End-Product Specific Receptor; RAGE; Receptor For Advanced Glycation End-Products Variant 20; Advanced Glycosylation End Product-Specific Receptor; Receptor For Advanced Glycosylation End Products; Receptor For Advanced Glycation End-Products; RAGE Isoform NtRAGE-Delta; RAGE Isoform SRAGE-Delta; SCARJ1

Background
The advanced glycosylation end product (AGE) receptor encoded by this gene is a member of the immunoglobulin superfamily of cell surface receptors. It is a multiligand receptor, and besides AGE, interacts with other molecules implicated in homeostasis, development, and inflammation, and certain diseases, such as diabetes and Alzheimer's disease. Many alternatively spliced transcript variants encoding different isoforms, as well as non-protein-coding variants, have been described for this gene (PMID:18089847).
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