Chondroitin Sulfate

Full Name

Chondroitin Sulfate

Keywords

Chondroitin Sulfate; -{GlcAb1-3(HSO3-4)GalNAcb1-4}n-

Background

Chondroitin sulfate, a polysaccharide moiety of proteoglycans, is one of the major components of the extracellular matrix of the animal body, and is composed of the repeating unit, [→4GlcA 1→3GalNAc 1→], commonly sulfated at the C-4 and/or C-6 of GalNAc. In the central nervous system, the most abundant glycosaminoglycan is chondroitin sulfate rich in [GlcA-GalNAc(4S)], namely chondroitin sulfate A. Chondroitin sulfate polysaccharides are involved in various cellular events in the formation, regeneration, and maintenance of the neural network. This monoclonal antibody recognizes effectively chondroitin sulfate A, especially the glycosaminoglycan existing in the developing central nervous system.