Polypeptide N-Acetylgalactosaminyltransferase 12; Polypeptide GalNAc Transferase 12; UDP-N-Acetyl-Alpha-D-Galactosamine:Polypeptide N-Acetylgalactosaminyltransferase 12 (GalNAc-T12); UDP-GalNAc:Polypeptide N-Acetylgalactosaminyltransferase 12; Protein-UDP Acetylgalactosaminyltransferase 12; Pp-GaNTase 12

This gene encodes a member of a family of UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferases, which catalyze the transfer of N-acetylgalactosamine (GalNAc) from UDP-GalNAc to a serine or threonine residue on a polypeptide acceptor in the initial step of O-linked protein glycosylation. Mutations in this gene are associated with an increased susceptibility to colorectal cancer.