2700086H06Rik; Glycogen Synthase Kinase 3 Alpha

Enables protein serine/threonine kinase activity and signaling receptor binding activity. Involved in several processes, including cell surface receptor signaling pathway; positive regulation of G protein-coupled receptor signaling pathway; and positive regulation of metabolic process. Acts upstream of with a positive effect on autosome genomic imprinting. Acts upstream of or within several processes, including cellular response to lithium ion; positive regulation of protein phosphorylation; and protein phosphorylation. Predicted to be located in microtubule. Predicted to be part of beta-catenin destruction complex. Predicted to be active in axon; cytosol; and nucleus. Is expressed in several structures, including alimentary system; bone; central nervous system; craniofacial suture; and early conceptus. Human ortholog(s) of this gene implicated in amyotrophic lateral sclerosis. Orthologous to human GSK3A (glycogen synthase kinase 3 alpha).