Glycophorin B (MNS Blood Group); SS-Active Sialoglycoprotein; Sialoglycoprotein Delta; PAS-3; GPB; Glycophorin B, Blood Group System Ss, S, Mit+; Glycophorin B/Glycophorin A Fusion Protein; Glycophorin B (Includes Ss Blood Group); Blood Group System MNSs, St(A) Type E; Blood Group System MNSs, St(A) Type F; Blood Group System MNSs, Mur-Like; Glycophorin B Blood Group Antigen; Glycophorin B (Ss Blood Group)

Glycophorins A (GYPA) and B (GYPB) are major sialoglycoproteins of the human erythrocyte membrane which bear the antigenic determinants for the MN and Ss blood groups. GYPB gene consists of 5 exons and has 97% sequence homology with GYPA from the 5' UTR to the coding sequence encoding the first 45 amino acids. In addition to the M or N and S or s antigens, that commonly occur in all populations, about 40 related variant phenotypes have been identified. These variants include all the variants of the Miltenberger complex and several isoforms of Sta; also, Dantu, Sat, He, Mg, and deletion variants Ena, S-s-U- and Mk. Most of the variants are the result of gene recombinations between GYPA and GYPB. Alternate splicing results in multiple transcript variants.