HYAL1

Full Name
Hyaluronoglucosaminidase 1

Keywords
Fus2; Hya1; Nat6; Hyal-1; Hyaluronoglucosaminidase 1

Background
Enables chondroitin hydrolase activity and hyalurononglucosaminidase activity. Involved in chondroitin sulfate proteoglycan catabolic process; hyaluronan catabolic process; and response to virus. Acts upstream of or within embryonic skeletal joint morphogenesis. Is active in lysosome. Is expressed in liver; metanephros; and renal tubule. Used to study mucopolysaccharidosis IX. Human ortholog(s) of this gene implicated in mucopolysaccharidosis and mucopolysaccharidosis IX. Orthologous to human HYAL1 (hyaluronidase 1).
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