ITIH4

Full Name

Inter-alpha-trypsin inhibitor heavy chain 4

Keywords

H4P; IHRP; GP120; PK120; ITIHL1; PK-120; ITI-HC4; inter-alpha-trypsin inhibitor heavy chain H4; ITI heavy chain H4; inter-alpha (globulin) inhibitor H4 (plasma Kallikrein-sensitive glycoprotein); inter-alpha-inhibitor heavy chain 4; inter-alpha-trypsin inhibitor family heavy chain-related protein; inter-alpha-trypsin inhibitor heavy chain family member 4; inter-alpha-trypsin inhibitor, heavy chain-like, 1; plasma kallikrein-sensitive glycoprotein 120

Background

The protein is secreted into the blood, where it is cleaved by plasma kallikrein into two smaller forms. Expression of this gene has been detected only in liver, and it seems to be upregulated during surgical trauma. This gene is part of a cluster of similar genes on chromosome 3.