Mannosidase Alpha Class 2A Member 1; Mannosyl-Oligosaccharide 1,3-1,6-Alpha-Mannosidase; Golgi Integral Membrane Protein 7; Golgi Alpha-Mannosidase II; EC 3.2.1.114; AMan II; MANA2; Mannosidase, Alpha, Class 2A, Member 1

This gene encodes a glycosyl hydrolase that localizes to the Golgi and catalyzes the final hydrolytic step in the asparagine-linked oligosaccharide (N-glycan) maturation pathway. Mutations in the mouse homolog of this gene have been shown to cause a systemic autoimmune disease similar to human systemic lupus erythematosus.