MOG

Full Name

Myelin oligodendrocyte glycoprotein

Keywords

BTN6; BTNL11; MOGIG2; NRCLP7; myelin-oligodendrocyte glycoprotein; MOG AluA; MOG AluB; MOG Ig-AluB; MOG alpha-5

Background

The product of this gene is a membrane protein expressed on the oligodendrocyte cell surface and the outermost surface of myelin sheaths. Due to this localization, it is a primary target antigen involved in immune-mediated demyelination. This protein may be involved in completion and maintenance of the myelin sheath and in cell-cell communication.