Oncofetal fibronectin

Full Name

Oncofetal fibronectin

Keywords

Oncofetal fibronectin; Fibronectin; glycoprotein

Background

Fibronectin is a high-molecular weight (~440kDa) glycoprotein of the extracellular matrix that binds to membrane-spanning receptor proteins called integrins. Fibronectin also binds to other extracellular matrix proteins such as collagen, fibrin, and heparan sulfate proteoglycans (e.g. syndecans).