PIGX

Full Name

Phosphatidylinositol glycan anchor biosynthesis class X

Keywords

PIG-X; Phosphatidylinositol glycan anchor biosynthesis class X

Background

This gene encodes a type I transmembrane protein in the endoplasmic reticulum (ER). The protein is an essential component of glycosylphosphatidylinositol-mannosyltransferase I, which transfers the first of the four mannoses in the GPI-anchor precursors during GPI-anchor biosynthesis. Studies in rat indicate that the protein is translated from a non-AUG translation initiation site.