SGCB

Full Name

Sarcoglycan beta

Keywords

A3b; LGMD2E; SGC; Sarcoglycan beta

Background

This gene encodes a member of the sarcoglycan family. Sarcoglycans are transmembrane components in the dystrophin-glycoprotein complex which help stabilize the muscle fiber membranes and link the muscle cytoskeleton to the extracellular matrix. Mutations in this gene have been associated with limb-girdle muscular dystrophy.