Slc2a4

GT2; twgy; Glut4; Glut-4; Solute Carrier Family 2 (Facilitated Glucose Transporter), Member 4

Enables D-glucose transmembrane transporter activity. Involved in glucose import in response to insulin stimulus. Acts upstream of or within several processes, including amylopectin biosynthetic process; brown fat cell differentiation; and cellular response to tumor necrosis factor. Located in several cellular components, including cytoplasmic vesicle; extracellular exosome; and sarcolemma. Is expressed in several structures, including adipose tissue; alimentary system; central nervous system; genitourinary system; and sensory organ. Used to study type 2 diabetes mellitus. Human ortholog(s) of this gene implicated in type 2 diabetes mellitus. Orthologous to human SLC2A4 (solute carrier family 2 member 4).