TRA-1-60

Full Name

TRA-1-60 (Podocalyxin)

Keywords

TRA-1-60 (Podocalyxin); TRA-1-60; Podocalyxin; Keratan C; KS; Keratan Sulfate, Lewis C

Background

TRA-1-60 is a cell surface antigen, expressed along with SSEA-3, SSEA-4 and TRA-1-81 in human embryonic stem cells, embryonal carcinoma cells and induced pluripotent stem cells (iPS). These surface markers are lost during the differentiation process. In contrast, SSEA-1 is absent in undifferentiated human stem cells but is present on the cell surface after retinoic acid mediated differentiation.