UDP Glucuronosyltransferase Family 2 Member B4; Hyodeoxycholic Acid-Specific UDPGT; EC 2.4.1.17; UDPGT 2B4; UDPGTh-1; UGT2B11; HLUG25; UDP Glucuronosyltransferase 2 Family, Polypeptide B4

UDPGTs are of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. This isozyme is active on polyhydroxylated estrogens (such as estriol, 4-hydroxyestrone and 2-hydroxyestriol) and xenobiotics (such as 4-methylumbelliferone, 1-naphthol, 4-nitrophenol, 2-aminophenol, 4-hydroxybiphenyl and menthol). It is capable of 6 alpha-hydroxyglucuronidation of hyodeoxycholic acid.