VCAN

Full Name

Versican

Keywords

WGN; ERVR; GHAP; PG-M; WGN1; CSPG2; versican core protein; chondroitin sulfate proteoglycan core protein 2; glial hyaluronate-binding protein; large fibroblast proteoglycan; versican proteoglycan

Background

It is a member of the aggrecan/versican proteoglycan family. The protein encoded is a large chondroitin sulfate proteoglycan and is a major component of the extracellular matrix. This protein is involved in cell adhesion, proliferation, proliferation, migration and angiogenesis and plays a central role in tissue morphogenesis and maintenance. Mutations in this gene are the cause of Wagner syndrome type 1.