XRN1

RGD1309713; 5'-3' Exoribonuclease 1

Predicted to enable 5'-3' RNA exonuclease activity; G-quadruplex DNA binding activity; and RNA binding activity. Involved in several processes, including cellular response to cycloheximide; cellular response to puromycin; and response to testosterone. Located in P-body; dendrite; and neuronal cell body. Human ortholog(s) of this gene implicated in Alzheimer's disease. Orthologous to human XRN1 (5'-3' exoribonuclease 1).