Carlumab (CAT#: TAB-117)

Datasheet

DESCRIPTION	CATALOG #	SIZE	PRICE
Anti-Human MCP-1 Recombinant Antibody	TAB-117	1mg	Please Inquiry

PRODUCT INFORMATION

Product Overview
Recombinant monoclonal antibody to MCP-1. Crenezumab is a humanized monoclonal antibody against human 1-40 and 1-42 Beta amyloid, which is being investigated as a treatment of Alzheimer's disease.

Applications
Suitable for use in ELISA, IP, FC, FuncS, Neut, IF, ICC and most other immunological methods.

Protein Construction
Immunoglobuline G2-kappa, anti-[Homo sapiens IL17RA (récepteur A de l"interleukine 17, CD217)], Homo sapiens anticorps monoclonal

Antigen Description
Chemotactic factor that attracts monocytes and basophils but not neutrophils or eosinophils. Augments monocyte anti-tumor activity. Has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis or atherosclerosis. May be involved in the recruitment of monocytes into the arterial wall during the disease process of atherosclerosis.

Function
CCR2 chemokine receptor binding; CCR2 chemokine receptor binding; G-protein coupled receptor binding; chemokine activity; heparin binding; protein kinase activity; receptor binding;

Synonyms
CCL2; chemokine (C-C motif) ligand 2; SCYA2, small inducible cytokine A2 (monocyte chemotactic protein 1, homologous to mouse Sig je); C-C motif chemokine 2; GDCF 2; HC11; MCAF; MCP 1; MCP1; MGC9434; monocyte chemoattractant protein 1; monocyte chemotactic and activating factor; monocyte chemotactic protein 1; homologous to mouse Sig je; monocyte secretory protein JE; small inducible cytokine subfamily A (Cys Cys); member 2; SMC CF; small-inducible cytokine A2; monocyte chemoattractant protein-1; small inducible cytokine subfamily A (Cys-Cys), member 2; small inducible cytokine A2 (monocyte chemotactic protein 1, homologous to mouse Sig-je); MCP-1; SCYA2; GDCF-2; SMC-CF; HSMCR30;

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