Genome editing screening can precisely modify the genome of cells or organisms to simulate the infection process and anti-infective effects, thus researching and screening for anti-infective hits. Creative Biolabs provides efficient genome editing screening services and innovative research models to assist clients in anti-infect hit discovery.
Fig. 1 Co-correlation analysis screens for genes of interest that are in the same cell survival pathway.1
1. Construct genome-wide target screening libraries.
With knowledge of your research background, experimental purpose and gene editing screening method, we will utilize gene editing tools to construct genome-wide target screening libraries, covering all genes and non-coding regions.
2. Infection model screening.
We would screen genome-wide target screening libraries with your requested infection model to identify genes that are inhibitory to the infection model.
3. Genome editing validation and optimization.
Validate and optimize the potential pharmaceutical targets screened, with performing precise genome editing validations, dose-response curve determinations, etc.
4. Data analysis and interpretation.
We will conduct a comprehensive data analysis of the experimental results and provide target screening results to help you interpret the results, explain possible effects, and inform the direction of subsequent experiments.
Creative Biolabs provides genome editing screening services aimed at screening potential drug targets associated with infectious diseases on a genome-wide scale. If you are interested in our genome editing screening service or have any questions, please feel free to contact us.
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