This product is a Raji B cell engineering tool based on the Nanoparticles (Mannose/Mannose receptor) delivery system and CRISPR-based (SHS-323-SpCas9-Cas9-L755507 ) genome editor.
| Host Cell | Raji |
| Target | 14-3-3 Pan |
| Insert Clone | 22-IID8B |
| Safe Harbor Sites (SHS) | SHS-323 |
| gRNA | SpCas9 |
| Nuclease | Cas9 |
| Enhancer | L755507 |
| Targeting Strategy | pH-dependent |
| Insertion sites | Human genome |
| Vehicles | Nanoparticles |
| Ligand/Receptor | Mannose/Mannose receptor |
| Active Agents | [Ru(bpy)2(tip)]2+, RBT |
| Particle Size | 20-150 |
| Charge (mv) | 10 to 100 |
| Total Atom Count | ~30,000,000 |
| Surface Atoms (%) | ~1.7 |
| Specific Surface Area (m2/g) | ~5.5 |
| Vector Type | Lentivirus |
| Vector Name | BCpCDH2 |
| Targeting Diseases | Breast cancer; Lung cancer; Colorectal cancer |
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