This product is a Farage B cell engineering tool based on the Gold nanoparticles (Folate/ Folate Receptor) delivery system and CRISPR-based (CCR5-sgRNA-Cpf1-Brefeldin A ) genome editor.
| Host Cell | Farage |
| Target | 14-3-3 Pan |
| Insert Clone | 60CRT10 |
| Safe Harbor Sites (SHS) | CCR5 |
| gRNA | sgRNA |
| Nuclease | Cpf1 |
| Enhancer | Brefeldin A |
| Targeting Strategy | Enzyme responsive |
| Insertion sites | Unproductive heavy chain |
| Vehicles | Gold nanoparticles |
| Ligand/Receptor | Folate/ Folate Receptor |
| Active Agents | Celastrol |
| Particle Size | 20-3500 |
| Charge (mv) | −5 to -40 |
| Total Atom Count | ~90,000,000 |
| Surface Atoms (%) | ~0.6 |
| Specific Surface Area (m2/g) | ~1.2 |
| Vector Type | Adenoviruses |
| Vector Name | BCpCDH3 |
| Targeting Diseases | Breast cancer; Lung cancer; Colorectal cancer |
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