5T4 mAb (39A11G5F2) RPMI 8226 B Cell Engineering Cassette (CAT#: BGS-0124-CR22)

This product is a RPMI 8226 B cell engineering tool based on the Nanoparticles (Mannose/Mannose receptor) delivery system and CRISPR-based (AAVS1-tracr RNA-Cas9-(Z)-4-Hydroxytamoxifen ) genome editor.

Datasheet

Specifications

Host Cell RPMI 8226
Target 5T4
Insert Clone 39A11G5F2
Safe Harbor Sites (SHS) AAVS1
gRNA tracr RNA
Nuclease Cas9
Enhancer (Z)-4-Hydroxytamoxifen
Targeting Strategy Enzyme responsive, time-dependent
Insertion sites Large DNA sequences
Vehicles Nanoparticles
Ligand/Receptor Mannose/Mannose receptor
Active Agents AntimiR-21, doxorubicin (DOX)
Particle Size <500
Charge (mv) <-1
Total Atom Count ~65,000,000
Surface Atoms (%) ~0.6
Specific Surface Area (m2/g) ~0.8
Vector Type MSCV
Vector Name BCpCDH6
Targeting Diseases Breast cancer; Lung cancer
COA

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! For Research Use Only | Not For Clinical Use

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