This product is a Raji B cell engineering tool based on the Nanoparticles (Tumor-homingpeptide tLyp-1/NRP-1) delivery system and CRISPR-based (SHS-317-tracr RNA-Cas9-Nocodazole ) genome editor.
| Host Cell | Raji |
| Target | ABCC8 |
| Insert Clone | BCRS-4921 |
| Safe Harbor Sites (SHS) | SHS-317 |
| gRNA | tracr RNA |
| Nuclease | Cas9 |
| Enhancer | Nocodazole |
| Targeting Strategy | Enzyme responsive |
| Insertion sites | Large DNA sequences |
| Vehicles | Nanoparticles |
| Ligand/Receptor | Tumor-homing peptide tLyp-1/NRP-1 |
| Active Agents | Paclitaxel, chlorin e6 |
| Particle Size | <500 |
| Charge (mv) | −10 to -50 |
| Total Atom Count | ~65,000,000 |
| Surface Atoms (%) | ~0.6 |
| Specific Surface Area (m2/g) | ~0.8 |
| Vector Type | RABV |
| Vector Name | BCpCDH8 |
| Targeting Diseases | Breast cancer; Lung cancer; Brain cancer; Colon cancer; Ovarian cancer |
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