B Cell Engineering Service for Anti-Germ Cell Tumor Antibody Delivery

Creative Biolabs is dedicated to providing exclusive B cell engineering service for anti-germ cell tumor delivery to facilitate your project's success.

The Introduction of Germ Cell Tumor

Germ cell tumor (GCT) is one of the most common solid malignancies with a remarkable 5-year survival rate of approximately 95%, affecting young men between the ages of 20 and 40 years. The global incidence of germ cell tumors has been increasing over the past few decades. A variety of cancer treatment approaches including surgery, chemotherapy, radiotherapy, and target therapies have been studied in high cure rates in patients with metastatic disease.

The rationale of germ cell tumor. Fig.1 The rationale of germ cell tumor. (Creative Biolabs)

B Cell Engineering Service for Anti-Germ Cell Tumor Antibody Delivery

Monoclonal antibody target to germ cell tumor is a rapidly developing class of GCTs therapeutic drugs, but a major limitation associated with this treatment is the need for repeated administration, often over years or decades, which usually involves intravenous infusion in ambulatory care centers. To avoid the need for repeated administration of Abs, genetically engineered B cells open up a new avenue to use B cells to treat disease. Powered by our strong expertise in cell engineering, Creative Biolabs provides comprehensive B cell engineering service for anti-germ cell tumor antibody delivery.

Key Features

  • Cell Banking System with Stringent Quality Control to Assist B Cell Engineering Service
    B cells as an attractive candidate for gene therapy due to their ease of isolation from peripheral blood, rapid growth, and ability to transform into long-living plasma cells that produce high levels of protein. The control of the quality system is very important in the process of using B cells, which will determine the state of the cell and affect whether the subsequent operation can be carried out normally. Based on our many years of laboratory experience, Creative Biolabs provides a one-stop, stringent quality control system throughout the B cell-related laboratory process to assist B cell engineering service.
  • The main experimental diagram related to B cells service. Fig.2 The main experimental diagram related to B cells service. (Creative Biolabs)

  • A Wide Genetics Platform to Enable B Cell Engineering with One-Stop Service
    Genetic approaches allow for rapid and precise genome engineering, and B cell engineering for anti-germ cell tumor antibody delivery is a particularly noteworthy application of the technology. Creative Biolabs offers the following highly effective genetic methods for clients to choose from.

  • Hot Targets Profile to Empower B Cell Engineering Service for Anti-Germ Cell Tumor Antibody Delivery
    We developed B cell engineering services for anti-germ cell tumor antibody delivery with a wide range of hot targets, by targeting specific pathways. The following are different exciting targets you can choose to engineer, including but not limited to:
  • Highly effective genetic methods.

For more details about our B cell engineering service for anti-sarcoma antibody delivery, please don't hesitate to contact us for more information.

Reference
  1. Greiner, V.; et al. CRISPR-mediated editing of the B cell receptor in primary human B cells. Iscience. 2019, 12: 369-78.

Related Sections: