B Cell Engineering Service for Anti-Glioma Antibody Delivery

Supported by in-house scientists and a first-in-class technological platform, Creative Biolabs has expanded our service capabilities to offer fully integrated B cell engineering service for anti-glioma antibody delivery to best suit the client's program requirements.

Background of Anti-Glioma Therapeutics

Glioblastoma (GBM) is a common and aggressive malignant tumor of the central nervous system (CNS), characterized by complex molecular heterogeneity and invasive growth. Although trials of novel drugs have been going on for decades, the median survival of patients has remained unchanged at 14~17 months. In recent years, many researchers have focused on the GBM immunity cycle, which has generated many new targeted therapy options.

The GBM immunity cycle and associated targeted therapy options. Fig.1 The GBM immunity cycle and associated targeted therapy options. (Bausart, et al., 2022)

B Cell Engineering Service for Anti-Glioma Antibody Delivery

Leveraging our expertise and experience, Creative Biolabs is committed to providing B cell engineering services for anti-glioma antibody delivery to accelerate glioma antibody research. We are proud to offer integrated research portfolio services for global customers to meet your research needs. The following is our workflow for our one-stop B cell engineering service. Every step of our operation will have strict quality control, from cell isolation to final verification.

The main workflow for the one-stop B cell engineering service. Fig.2 The main workflow for the one-stop B cell engineering service. (Creative Biolabs)

Key Features

  • A Wide Range of Genetic Methods for B Cell Engineering Service
    Creative Biolabs provides a one-stop platform to accelerate research of engineering B cells for therapeutics delivery, characterized by a wide range of genetic methods for B cell engineering service. There are some attractive genetic methods you can choose to design for:
  • Several Hot Targets of B Cell Engineering Service for Anti-Glioma Antibody Delivery
    As more and more glioma markers have been identified, we have rolled out B-cell engineering services for anti-glioma antibody delivery with a wide range of popular targets. Here are some efficient targets you can choose to design for, including but not limited to:
Targeting Neoantigen GD2; IL13Rα2; HER2; EphA2; Survivin; TRP2; WT1; gp100; SOX2; SOX11; MAGE-A1; AIM2; EGFRvIII; Chlorotoxin; CD70; CD133......
Targeting TME PD-1; PD-L1; IDO; CD47; CD40; CXCR4; CD73......

Working with Creative Biolabs

Creative Biolabs is committed to providing high-quality, efficient, and integrative study assay portfolio services to help our clients shorten their research journey.

For more detailed information on B cell engineering service for anti-glioma antibody delivery, please feel free to contact us or directly sent us an inquiry.

Reference
  1. Bausart, M.; et al. Immunotherapy for glioblastoma: the promise of combination strategies. Journal of Experimental & Clinical Cancer Research. 2022, 41(1): 35.

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