This product is a Ramos (RA 1) B cell engineering tool based on the Micelles (MUC1 aptamer/MUC1) delivery system and CRISPR-based (hROSA26-huIgH296-Cas12-3'-Azido-3'-deoxythymidine ) genome editor.
| Host Cell | Ramos (RA 1) |
| Target | GITR |
| Insert Clone | 5h7 |
| Safe Harbor Sites (SHS) | hROSA26 |
| gRNA | huIgH296 |
| Nuclease | Cas12 |
| Enhancer | 3'-Azido-3'-deoxythymidine |
| Targeting Strategy | pH responsive |
| Insertion sites | Nonhomologous target sites |
| Vehicles | Micelles |
| Ligand/Receptor | MUC1 aptamer/MUC1 |
| Active Agents | [Ru(bpy)2(tip)]2+, RBT |
| Particle Size | 20-150 |
| Charge (mv) | ≤50 |
| Total Atom Count | ~60,000,000 |
| Surface Atoms (%) | ~0.8 |
| Specific Surface Area (m2/g) | ~2.5 |
| Vector Type | AAV |
| Vector Name | BCpCDH1 |
| Targeting Diseases | Breast cancer; Lung cancer; Pancreatic cancer |
Certificate of Analysis Lookup
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.