This product is a Jiyoye [Jijoye, P-2003, P-3J] B cell engineering tool based on the Nanoparticles (MUC1 aptamer/MUC1) delivery system and CRISPR-based (CCR5-tracr RNA-Cas9-Brefeldin A) genome editor.
| Host Cell | Jiyoye [Jijoye, P-2003, P-3J] |
| Target | GITR |
| Insert Clone | BG-65F |
| Safe Harbor Sites (SHS) | CCR5 |
| gRNA | tracr RNA |
| Nuclease | Cas9 |
| Enhancer | Brefeldin A |
| Targeting Strategy | pH responsive, mucoadhesiveness |
| Insertion sites | Unproductive heavy chain |
| Vehicles | Nanoparticles |
| Ligand/Receptor | MUC1 aptamer/MUC1 |
| Active Agents | Thymoquinone |
| Particle Size | 10-50 |
| Charge (mv) | -15 to -310 |
| Total Atom Count | -64,000,000 |
| Surface Atoms (%) | -0.5 |
| Specific Surface Area (m2/g) | -0.7 |
| Vector Type | Adenoviruses |
| Vector Name | BCpCDH3 |
| Targeting Diseases | Breast cancer; Lung cancer; Pancreatic cancer |
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