The product is a highly efficient, inducible WT Cas9-ASGR1 gene-editing based novel Lentivirus packaging system that can be used to mediate researches involving anti-TNFSF12 mab (BGF15) in Rat B cell engineering.
| Clone | BGF15 |
| Host | Humanized |
| Packaging Cell Line | GP-293 |
| Vector Promoter | CMV |
| Rep | Rep52 |
| Capsid | VP3 |
| Envelope | VSV-G |
| Matrix | N-terminal |
| Size | ~30kb |
| Genome | dsDNA |
| Virus Type | Lentivirus |
| Cofactor Requirement | No ATP, CP, or CPK |
| Particles/mL | 3.3 × 10¹¹ |
| PFU/mL | 6.6 × 10¹¹ |
| TU/mL | 6.6 × 10¹¹ |
| Cas9 | WT Cas9 |
| sgRNA | ASGR1 |
| Engineered B Cell | Rat B cells |
| Target | TNFSF12 |
| Alternative Names | TNFSF12; APO3L; DR3LG; TWEAK; TNLG4A; tumor necrosis factor superfamily member 12; TNF superfamily member 12 |
| Format | Liquid |
| Shipping | The product is shipped by dry ice. |
| Storage | Upon receipt, store immediately at -80°C or lower for long-term storage. Avoid freeze/thaw cycles. |
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