RUNX1 mAb (7UL5) B Cell Engineering Specific Plasmid (CAT#: BGS-1223-CR6)

This product is a B cell engineering plasmid designed by genomic integration of B cell receptors (GFP-CMV-Tat/SPI-CD79α-CD28-His) and CRISPR-Cas (SaCas9-dsDNA-HD/Cas3-Stat5a) systems. This product can precisely introduce cassettes of several kb size into the genome of various B cells to enhance surface expression and antigen recognition of a synthetic BCRs.

Datasheet

Specifications

Clone 7UL5
Host Mouse
Targeting Cell Type Raji
Reporter gene GFP
Promoter CMV
Signal peptides Tat/SPI
Signaling domains CD79α
TM domains CD28
Detection tags His
Linkers Thioredoxin with polylinker
Co-Receptors CD22
Vector Type RABV
Vector Name BGpCDH8
Class 2 single-Cas
Type
Subtype A, B, C, D, E, F, U
Effector SaCas9
DNA Type dsDNA
Nuclease domains HD/Cas3
TracrRNA requirement YES
PAM/PFS -
Insertion Stat5a
Construction GFP-CMV-CD79α-SaCas9-dsDNA-Stat5a

Target Information

Target RUNX1
Alternative Names RXFP1; LGR7; RXFPR1; Relaxin/insulin-like family peptide receptor 1; relaxin/insulin like family peptide receptor 1; relaxin family peptide receptor 1

Product Properties

Format Liquid/lyophilized
Shipping It is usually shipped overnight at room temperature in small cardboard boxes. If hot temperatures are expected during transit, they will be shipped in polystyrene containers with gel ice packs.
Handling Advice No special measures are necessary. Keep away from food, drink and animal feedingstuffs.
Storage Plasmid (lyophilized), short-time storage at Room Temperature, recommended store at -20°C or -80°C ; Plasmid (Liquid), blue ice store at 4°C.
COA

Certificate of Analysis Lookup

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