PRODUCT INFORMATION
Description
The C-terminal peptide CXCL8 (54-72), encompassing residues 54 to 72 of the chemokine, functions as a critical GAG-binding domain through charge-mediated interactions with negatively charged glycosaminoglycans (GAGs). This 19-amino acid fragment disrupts CXCL8 signaling by competitively inhibiting receptor binding and downstream inflammatory processes, demonstrating potential for studying chemokine modulation in neutrophil adhesion and endothelial cell migration.
Molecular Weight
2401.72
Purity
> 95%
Formula
C₁₀₇H₁₇₃N₃₃O₃₀
Product Type
Targeting Peptide
Sequence
Ac-Lys-Glu-Asn-Trp-Val-Gln-Arg-Val-Val-Glu-Lys-Phe-Leu-Lys-Arg-Ala-Glu-Asn-Ser-NH₂
Form (20 deg.C)
Solid
Storage Condition
Store sealed at -20°C, away from moisture.
For Research Use Only | Not For Clinical Use
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