Custom Peptide Synthesis & Modification Service
Making custom peptides (small protein pieces) is key for developing new medicines, bioengineering tools, and lab research. This process lets scientists create peptides that fight infections, target cancer, or perform other specific jobs. New improvements in peptide technology help researchers better study how these molecules work in the body, leading to scientific breakthroughs. Creative Biolabs stands ready as an innovative partner in peptide conjugation to support these endeavors.
How Can We Help?
Stuck getting pure, modified peptides for your drug or study? Finding peptide synthesis slow or tricky? Our service speeds things up by making peptides exactly how you need them. Using trusted chemical methods like solid-phase and liquid-phase synthesis, we deliver high-quality peptides so you can focus on your research, not lab hassles.
Our Services:
| Category | Types |
|---|---|
| Peptide Synthesis Types | General linear peptides, long peptides, etc. |
| Peptide Synthesis Scale | Milligram-scale, Gram-scale, and Custom Bulk Synthesis |
| Peptide Modification Types | N-terminal, C-terminal, and Amino Acid Modifications, Labeling, and PEGylation |
Workflow:
Creative Biolabs employs a streamlined and efficient workflow to ensure the successful synthesis and delivery of your custom peptides. Here is a thorough explanation of the main procedures involved:
| Steps | Description | Expected Outcome |
|---|---|---|
| Consultation and Design | We collaborate with you to comprehend the needs of your project, including peptide sequence, desired purity, modifications, and quantity. Our team designs the optimal synthesis strategy, considering factors such as peptide length, sequence complexity, and modification chemistry. | A clear synthesis plan with detailed sequence design, modification scheme, and quality specifications. |
| Synthesis | Creative Biolabs utilizes state-of-the-art solid-phase or liquid-phase synthesis methods, depending on the peptide sequence and complexity. We employ optimized protocols and high-quality reagents. Each synthesis step is monitored to maintain high fidelity and yield. | Synthesis of the crude peptide, meeting sequence and modification requirements. |
| Purification | The crude peptide undergoes purification through HPLC to eliminate any unwanted byproducts or impurities. We employ various HPLC techniques to achieve the desired purity level. | Purified peptide, meeting agreed-upon purity specifications (typically 75% to >98%). |
| Quality Control and Analysis | Rigorous quality control measures ensure the identity, purity, and integrity of the final product. We use MS and HPLC to confirm peptide sequence and purity. A COA is generated, providing detailed information. | A comprehensive COA, including HPLC and MS data, confirms peptide quality. |
| Delivery and Support | The purified and analyzed peptide is carefully packaged and shipped. We provide ongoing technical support and consultation. | Timely delivery of the high-quality peptide, with necessary documentation and support. |
Required Starting Materials:
- Peptide sequence.
- Desired purity level.
- Specific modification requirements (if any, e.g., phosphorylation, acetylation).
Final Deliverables:
- Purified, lyophilized peptide.
- A complete COA file containing HPLC and Mass spectrometry (MS) reports.
Estimated Timeframe:
3 ~ 6 weeks, depending on peptide sequence complexity, required purity, and modifications.
Why Choose Us?
- Unparalleled Expertise: Our team has a lot of knowledge in peptide chemistry, synthesis, and analysis. We have a history of successfully making complex peptides.
- Advanced Technology: We use the newest equipment and techniques, including solid-phase and liquid-phase synthesis, for the best efficiency and peptide quality.
- Customization and Flexibility: We make our services fit your needs. This includes making peptides of different lengths, purities, and modifications.
- Stringent Quality Control: We follow strict standards. Each peptide is thoroughly analyzed by HPLC and MS. A detailed COA is provided.
- Client-Centric Approach: We provide excellent customer service and support throughout the process.
Case Study
Explore our success stories through a detailed case study.
Case 1: Synthesis of a 29 AA linear peptide, MW 3862.35.
- Mass Analysis:
- HPLC Analysis: Conjugate purity >99%
Case 2: Synthesis of a 16 AA cyclic peptide, MW 2017.94.
- Mass Analysis:
- HPLC Analysis: Conjugate purity 100%
Case 3: Synthesis of a biotin-labeled 16 AA cyclic peptide, MW 2244.02.
- Mass Analysis:
- HPLC Analysis: Conjugate purity >99%
Customer Reviews
A***a:
"Creative Biolabs' peptide conjugation service was critical for our antibody-drug conjugate (ADC) development. The consistency and quality of the conjugated peptides significantly improved our results."
[4 Weeks]
R***d:
"We used Creative Biolabs' custom peptide synthesis with a specific linker for our nanoparticle targeting research. The high purity and precise modification allowed us to achieve excellent targeting efficiency."
[6 Weeks]
L***y:
"Creative Biolabs' team provided invaluable support in designing and synthesizing a complex peptide-dye conjugate for our live-cell imaging experiments. Their expertise and communication were exceptional."
[3 Weeks]
FAQs
1. Q: What peptide sizes and purity levels can you make?
A: We can create both short and long peptides. The purity can be basic (for early tests) or super clean (over 98%). Contact us to discuss your needs.
2. Q: What changes can you add to the peptides?
A: We add things like acetyl groups, amide ends, phosphate groups (for signaling), sugar chains, or glowing tags (to track them). Contact our team for details.
3. Q: How do I get a quote?
A: Provide your peptide sequence, desired purity, and modification requirements. We'll reply fast with a full quote.
4. Q: Can you make peptides in large amounts?
A: Yes, we handle tiny lab samples (milligrams) to big batches (grams or more). Need bulk? Let's plan your order!
Creative Biolabs is dedicated to providing high-quality custom peptides and services. Contact our team today to discuss your project and receive a personalized consultation to accelerate your research.