Cas No.: 1926163-30-5
PRODUCT INFORMATION
Description
This tumor-targeted pro-apoptotic peptide, CNGRC-GG-D(KLAKLAK)₂, integrates a tumor-homing CNGRC domain (targeting CD13) and a cytotoxic (KLAKLAK)₂ module. The (KLAKLAK)₂ moiety destabilizes mitochondrial membranes to induce caspase-dependent apoptosis in target cell lines. Its disulfide-bridged architecture enhances accumulation in research models, demonstrating potent in vitro cytotoxic activity.
Molecular Weight
2168.72
Purity
> 95%
Formula
C₉₄H₁₇₄N₃₂O₂₂S₂
Product Type
Targeting Peptide
Sequence
Cys-Asn-Gly-Arg-Cys-Gly-Gly-Lys-Leu-Ala-Lys-Leu-Ala-Lys-Lys-Leu-Ala-Lys-Leu-Ala-Lys-NH₂ (Disulfide bridge:Cys1-Cys5)
Form (20 deg.C)
Solid
Storage Condition
Store the product under the recommended conditions in the Certificate of Analysis (CoA).
For Research Use Only | Not For Clinical Use
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