VSLRGDTRG Targeting Peptide (CAT#: OLY-1025-YS-32)

Description

VSLRGDTRG is a synthetic RGD-containing peptide derived from cadherin 17 (CDH17) that binds α2β1 integrin. This binding stimulates its conformational activation, leading to enhanced β1 integrin affinity, FAK/ERK1/2 phosphorylation, and subsequent signaling in CDH17-expressing cell lines. This mechanism involves a CDH17-specific RGD-integrin interaction, which is studied for its role in coordinating dual ligand engagement with collagen IV.

Molecular Weight

960.05

Purity

> 95%

Formula

C₃₈H₆₉N₁₅O₁₄

Product Type

Targeting Peptide

Sequence

Val-Ser-Leu-Arg-Gly-Asp-Thr-Arg-Gly

Form (20 deg.C)

Solid

Storage Condition

Store the product under the recommended conditions in the Certificate of Analysis (CoA).