Under the background of the global COVID-19 pandemic, amazing progress has been made in the field of vaccine research and development, and there are more and more different types of vaccines basedRead More…
Cell Rep: mRNA Vaccine Technology May Help to Develop New HIV Vaccines
Using nucleoside modified mRNAs in lipid nanoparticles (mRNA-LNP) as a vaccine for COVID-19 may successfully predict a new era of vaccine development. For HIV-1, polyvalent enveloped trimer protein nanoparticles may be usedRead More…
Respiratory Syncytial Virus (RSV) Vaccine: Breakthrough Therapy RSVpreF Approved by FDA
Recently, the US Food and Drug Administration (FDA) has granted respiratory syncytial virus (RSV) bivalent pre-fused F subunit vaccine (RSVpreF) breakthrough therapy recognition (BTD), which is an active immunization for the pregnantRead More…
Nat Commun: Natural env Trimer Produces Tier-2 Neutralizing Antibodies Against HIV In Vivo
Nearly 40 years after the discovery of HIV, it has killed 36.3 million people, but so far there is still no effective vaccine available. In a new study, however, researchers from theRead More…
New strategy for vaccine development! Memory helper T cells perpetuate memory B cells that resist chronic viral infection
Viruses such as HIV or hepatitis C virus (HCV) can destroy the immune system. So far, one way to develop vaccines against these chronic infections is to target memory B cells, aRead More…
Improve tumor vaccination using farnesylthiosalicylic acid derivative PEI nanocomposite
Tumor vaccine is a promising therapeutic strategy, which produces long-term anti-tumor immunity by stimulating immune responses accordingly. However, due to inefficient vaccination, the clinical efficacy of such vaccines is limited. Recently, inRead More…
World’s first clinical trial of breast cancer vaccine launched
Researchers at the Cleveland Clinic in the United States launched a new vaccine study aimed at eventually preventing triple negative breast cancer, a highly invasive and deadly form of cancer. The vaccineRead More…
Breakthrough: Broad-spectrum Anti-infective Vaccine to Solve Microbial Drug Resistance
With the mounting number of drug-resistant microbial infections, the epidemic outbreak of pathogenic bacteria, and the possible threat of new organisms in the future, the clinical intervention of infectious diseases is facingRead More…
Nature Communication: Cancer vaccine may effectively overcome the drug tolerance of cancer cells
In the clinical trial of oncolytic vesicular stomatitis virus expressing interferon-β (VSV-IFN-β), a large group of patients initially achieved a preliminary response, but then the disease relapsed. A few days ago, inRead More…
Science sub-journal: vaccination of symbiotic bacteria expressing NadA can prevent meningitis caused by Neisseria meningitidis
In a recent study, researchers from the University of Southampton in the UK inserted a gene into a harmless bacteria that allowed it to stay in the nose for a long timeRead More…
