Home > Products > Ad fiber knob & CD40 > Recombinant Anti-Ad fiber knob x Anti-CD40 Bispecific Antibody (Single-chain Diabody)

Recombinant Anti-Ad fiber knob x Anti-CD40 Bispecific Antibody (Single-chain Diabody)  (SCDB-002)

Recombinant Anti-Ad fiber knob x Anti-CD40 Bispecific Antibody (Single-chain Diabody) is designed to be expressed as one polypeptide chain with four variable domains from two parental antibodies. The middle linker is long enough to form scFv dimers between the two diabody chains. This BsAb can retarget of adenoviral vectors to tumour cells. It can be used in cancer gene therapy to transfer a therapeutic gene into tumour cells aiming at selective and efficient cell killing.

Specifications

Targets
Ad fiber knob & CD40
Type
Single-chain Diabody
Species Reactivity
Human
Target 1
Ad fiber knob
Host Animal 1
Mouse
Target 2
CD40
Host Animal 2
Mouse
Application
FuncS; Promising therapeutic agent
Related Disease
Acute myeloid leukaemic (AML)

Targets

Target 1
Ad fiber knob
Alternative Names
Ad fiber knob; Adenovirus fiber knob; adenovirus fiber protein; knob domain of Ad fiber
Target 2
CD40
Gene ID
UniProt ID
Alternative Names
CD40; CD40 molecule; p50; Bp50; CDW40; TNFRSF5

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