Recombinant Anti-Ad fiber knob x Anti-CEA Bispecific Antibody (IgG-Fv) (BSGV-003)

Recombinant Anti-Ad fiber knob x Anti-CEA Bispecific Antibody (IgG-Fv) is formed by an Immunoglobulin G (IgG) and a fragment variable Fv region, in which the Fc of IgG is engineered by KIH. The Fv region of an anti-Ad fiber knob antibody variable domain is fused to the C terminal of an IgG of anti-CEA antibody, or vice versa. The format retains desired characteristics of intact antibodies. This BsAb can retarget of adenoviral vectors to tumour cells. It can be used in cancer gene therapy to transfer a therapeutic gene into tumour cells aiming at selective and efficient cell killing.

Datasheet INQUIRY

Specifications

Targets

Ad fiber knob & CEA

Type

IgG-Fv

Species Reactivity

Human

Application

FuncS; Promising therapeutic agent

Related Disease

Colorectal cancer (CRC); Gastric cancer; Pancreatic cancer; Lung cancer

Targets

Target 1

Ad fiber knob

Alternative Names

Ad fiber knob; Adenovirus fiber knob; adenovirus fiber protein; knob domain of Ad fiber

Target 2

CEA

Gene ID

1048

UniProt ID

A0A024R0K5

Alternative Names

CEACAM5; carcinoembryonic antigen; carcinoembryonic antigen related cell adhesion molecule 5; CEA; CD66e; meconium antigen 100

Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

Online Inquiry

Related products of "Ad fiber knob & CEA"

See other bsAb targets related to "Ad fiber knob"

See other bsAb targets related to "CEA"

Customer Reviews and Q&As

There are currently no customer reviews or questions for Recombinant Anti-Ad fiber knob x Anti-CEA Bispecific Antibody (IgG-Fv) (BSGV-003). Click the button below to contact us or submit your feedback about this product.

Recombinant Anti-Ad fiber knob x Anti-CEA Bispecific Antibody (IgG-Fv) (CAT#: BSGV-003)

Specifications

Targets

Customer Reviews and Q&As