Anti-Ad fiber knob x Anti-CEA Bispecific Antibody (IgG-IgG)  (BSIG-003)

Anti-Ad fiber knob x Anti-CEA Bispecific Antibody (IgG-IgG) is designed to be generated by crosslinking two full length IgGs, anti-Ad fiber knob and anti-CEA parental antibodies. A stable linkage is formed between the two antibodies. This BsAb can retarget of adenoviral vectors to tumour cells. It can be used in cancer gene therapy to transfer a therapeutic gene into tumour cells aiming at selective and efficient cell killing.

Datasheet