Recombinant Anti-Ad fiber knob x Anti-CEA Bispecific Antibody (scIgG) (SCIGG-003)

Recombinant Anti-Ad fiber knob x Anti-CEA Bispecific Antibody (scIgG) is designed to be expressed as two chains, each chain has the same units with their parental IgG antibodies, anti-Ad fiber knob and anti-CEA IgGs. The two chains form heterodimer via Fc KIH technology. This BsAb can retarget of adenoviral vectors to tumour cells. It can be used in cancer gene therapy to transfer a therapeutic gene into tumour cells aiming at selective and efficient cell killing.

Datasheet INQUIRY

Specifications

Targets

Ad fiber knob & CEA

Type

Single chain IgGs

Species Reactivity

Human

Application

FuncS; Promising therapeutic agent

Related Disease

Colorectal cancer (CRC); Gastric cancer; Pancreatic cancer; Lung cancer

Targets

Target 1

Ad fiber knob

Alternative Names

Ad fiber knob; Adenovirus fiber knob; adenovirus fiber protein; knob domain of Ad fiber

Target 2

CEA

Gene ID

1048

UniProt ID

A0A024R0K5

Alternative Names

CEACAM5; carcinoembryonic antigen; carcinoembryonic antigen related cell adhesion molecule 5; CEA; CD66e; meconium antigen 100

Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

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Recombinant Anti-Ad fiber knob x Anti-CEA Bispecific Antibody (scIgG) (CAT#: SCIGG-003)

Specifications

Targets

Customer Reviews and Q&As