Home > Products > Ad fiber knob & EPCAM > Recombinant Anti-Ad fiber knob x Anti-EPCAM Bispecific Antibody (Tandem scFv-Fc)

Recombinant Anti-Ad fiber knob x Anti-EPCAM Bispecific Antibody (Tandem scFv-Fc)  (BSFVF-004)

Recombinant Anti-Ad fiber knob x Anti-EPCAM Bispecific Antibody (Tandem scFv-Fc) is designed to be expressed as a homodimer, which has 2+2 antigen-binding valency. This format consists of one Fc region and two tandem scFv fragments, in which the anti-Ad fiber knob/EPCAM tandem scFv is fused to the Fc domain. The engineered fragment format is used to extend the half-life. This BsAb can retarget of adenoviral vectors to tumour cells. It can be used in cancer gene therapy to transfer a therapeutic gene into tumour cells aiming at selective and efficient cell killing.

Specifications

Targets
Ad fiber knob & EPCAM
Type
Constant Domain-extended Bispecific Fragments
Species Reactivity
Human
Target 1
Ad fiber knob
Host Animal 1
Mouse
Target 2
EPCAM
Host Animal 2
Mouse
Application
FuncS; Promising therapeutic agent
Related Disease
Breast cancer; Ovary cancer; Colon cancer; Lung cancer

Targets

Target 1
Ad fiber knob
Alternative Names
Ad fiber knob; Adenovirus fiber knob; adenovirus fiber protein; knob domain of Ad fiber
Target 2
EPCAM
Gene ID
UniProt ID
Alternative Names
EPCAM; epithelial cell adhesion molecule; ESA; KSA; M4S1; MK-1; DIAR5; EGP-2; EGP40; KS1/4; MIC18; TROP1; EGP314; HNPCC8; TACSTD1; epithelial glycoprotein 314; human epithelial glycoprotein-2; cell surface glycoprotein Trop-1; adenocarcinoma-associated antigen; tumor-associated calcium signal transducer 1; major gastrointestinal tumor-associated protein GA733-2; membrane component, chromosome 4, surface marker (35kD glycoprotein)

Customer Reviews and Q&As

There are currently no customer reviews or questions for Recombinant Anti-Ad fiber knob x Anti-EPCAM Bispecific Antibody (Tandem scFv-Fc) (BSFVF-004). Click the button below to contact us or submit your feedback about this product.

Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

Welcome! For price inquiries, we will get back to you as soon as possible.

To order, please email

INQUIRY
Related products of "Ad fiber knob & EPCAM"
See other bsAb targets related to "Ad fiber knob"

See other bsAb targets related to "EPCAM"

Online Inquiry

24x7 Service quality
USA

Tel:
Fax:
Email:

UK

Tel:
Email:

Germany

Tel:
Email: