Recombinant Anti-Ad fiber knob x Anti-ITGAV Bispecific Antibody (Fv-IgG) (BSDG-005)

Recombinant Anti-Ad fiber knob x Anti-ITGAV Bispecific Antibody (Fv-IgG) is an appended IgG format, which has 2+2 antigen-binding valency. This dual variable domain IgG is generated by appending variable domains of an anti-Ad fiber knob IgG with similar domains from an anti-ITGAV antibody via short peptide linkers, or vice versa. This BsAb can retarget of adenoviral vectors to tumour cells. It can be used in cancer gene therapy to transfer a therapeutic gene into tumour cells aiming at selective and efficient cell killing.

Datasheet INQUIRY

Specifications

Targets

Ad fiber knob & ITGAV

Type

Appended IgGs

Species Reactivity

Human

Application

FuncS; Promising therapeutic agent

Related Disease

Colorectal cancer (CRC); Prostate cancer; Ovarian cancer

Targets

Target 1

Ad fiber knob

Alternative Names

Ad fiber knob; Adenovirus fiber knob; adenovirus fiber protein; knob domain of Ad fiber

Target 2

ITGAV

Gene ID

3685

UniProt ID

P06756

Alternative Names

ITGAV; integrin, alpha V; CD51; MSK8; VNRA; VTNR; integrin alpha-V; integrin alphaVbeta3; vitronectin receptor subunit alpha; antigen identified by monoclonal antibody L230; integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51)

Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

Online Inquiry

Related products of "Ad fiber knob & ITGAV"

See other bsAb targets related to "Ad fiber knob"

Customer Reviews and Q&As

There are currently no customer reviews or questions for Recombinant Anti-Ad fiber knob x Anti-ITGAV Bispecific Antibody (Fv-IgG) (BSDG-005). Click the button below to contact us or submit your feedback about this product.

Recombinant Anti-Ad fiber knob x Anti-ITGAV Bispecific Antibody (Fv-IgG) (CAT#: BSDG-005)

Specifications

Targets

Customer Reviews and Q&As