Home > Products > albumin & IL-6R > Recombinant Human Anti-albumin x Human Anti-IL-6R Bispecific Antibody (F(ab')2-scFv2)

Recombinant Human Anti-albumin x Human Anti-IL-6R Bispecific Antibody (F(ab')2-scFv2)  (BABFV-H194)

Recombinant Anti-albumin x Anti-IL-6R Bispecific Antibody (F(ab')2-scFv2) is designed to be expressed as two chains combined via a hinge region. The scFv of the anti-albumin specificity is fused to the C terminus of the anti-IL-6R Fab fragment, or vice versa. This format comprises four binding sites (two same scFv regions and two same Fab fragments), two for each antigen. This BsAb can act as PK-modulated receptor antagonist. It is designed for the research of Lupus, rheumatoid arthritis therapy.

Specifications
Targets
albumin & IL-6R
Type
Fab-Fc Fusion Proteins
Species Reactivity
Human
Target 1
albumin
Host Animal 1
Human
Target 2
IL-6R
Host Animal 2
Human
Application
FuncS; Promising therapeutic agent
Related Disease
Systemic lupus erythematosus (SLE); Rheumatoid arthritis (RA)
Targets
Target 1
albumin
Gene ID
UniProt ID
Alternative Names
ALB; albumin; HAS; PRO0883; PRO0903; PRO1341
Target 2
IL-6R
Gene ID
UniProt ID
Alternative Names
IL6R; IL-6R; interleukin 6 receptor; IL6Q; gp80; CD126; IL6RA; IL6RQ; IL-6RA; IL-6R-1
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