Home > Products > albumin & IL-6R > Recombinant Anti-albumin x Anti-IL-6R Bispecific Antibody (Miniantibody)

Recombinant Anti-albumin x Anti-IL-6R Bispecific Antibody (Miniantibody)  (MNAB-H194)

Recombinant Anti-albumin x Anti-IL-6R Bispecific Antibody (Miniantibody) is a fusion protein of two scFv fragments combined with distinct specificity. One scFv of an anti-albumin antibody variable domain is linked to another scFv of an anti-IL-6R antibody variable domain by a flexible hinge region. This BsAb format has the decreased size and better penetration than conventional IgGs in the clinical diagnostics and potentially therapy. This BsAb can act as PK-modulated receptor antagonist. It is designed for the research of Lupus, rheumatoid arthritis therapy.

Specifications
Targets
albumin & IL-6R
Type
scFv-based Bispecific Fragments
Species Reactivity
Human
Target 1
albumin
Host Animal 1
Mouse
Target 2
IL-6R
Host Animal 2
Mouse
Application
FuncS; Promising therapeutic agent
Related Disease
Systemic lupus erythematosus (SLE); Rheumatoid arthritis (RA)
Targets
Target 1
albumin
Gene ID
UniProt ID
Alternative Names
ALB; albumin; HAS; PRO0883; PRO0903; PRO1341
Target 2
IL-6R
Gene ID
UniProt ID
Alternative Names
IL6R; IL-6R; interleukin 6 receptor; IL6Q; gp80; CD126; IL6RA; IL6RQ; IL-6RA; IL-6R-1

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