Recombinant Anti-albumin x Anti-IL-6R Bispecific Antibody (Minibody) is designed to be expressed as the anti-albumin scFv fused to N-terminus of Knob-CH3 domain and the anti-IL-6R scFv to the Hole-CH3 domain, or vice versa. The CH3 domains are further stabilized by C-terminal disulfide bonds. This BsAb can act as PK-modulated receptor antagonist. It is designed for the research of Lupus, rheumatoid arthritis therapy.
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