Home > Products > albumin & IL-6R > Recombinant Anti-albumin x Anti-IL-6R Bispecific Antibody (scFv-Fc)

Recombinant Anti-albumin x Anti-IL-6R Bispecific Antibody (scFv-Fc)  (BSCFV-006)

Recombinant Anti-albumin x Anti-IL-6R Bispecific Antibody (scFv-Fc) is formed by fusing two different scFv fragments to the hinge and Fc regions, in which the Fc region are engineered by KIH. Two of scFv moiety has the antibody variable domain of either anti-albumin specificity or anti-IL-6R specificity, which produces bivalent IgG-like molecules with desired characteristics of intact antibodies. This BsAb can act as PK-modulated receptor antagonist. It is designed for the research of Lupus, rheumatoid arthritis therapy.

Specifications
Targets
albumin & IL-6R
Type
scFv-based Bispecific Fragments
Species Reactivity
Human
Target 1
albumin
Host Animal 1
Mouse
Target 2
IL-6R
Host Animal 2
Mouse
Application
FuncS; Promising therapeutic agent
Related Disease
Systemic lupus erythematosus (SLE); Rheumatoid arthritis (RA)
Targets
Target 1
albumin
Gene ID
UniProt ID
Alternative Names
ALB; albumin; HAS; PRO0883; PRO0903; PRO1341
Target 2
IL-6R
Gene ID
UniProt ID
Alternative Names
IL6R; IL-6R; interleukin 6 receptor; IL6Q; gp80; CD126; IL6RA; IL6RQ; IL-6RA; IL-6R-1

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