Recombinant Human Anti-albumin x Human Anti-IL-6R Bispecific Antibody (scFv-Fc) (BSCFV-H194)

Recombinant Anti-albumin x Anti-IL-6R Bispecific Antibody (scFv-Fc) is formed by fusing two different scFv fragments to the hinge and Fc regions, in which the Fc region are engineered by KIH. Two of scFv moiety has the antibody variable domain of either anti-albumin specificity or anti-IL-6R specificity, which produces bivalent IgG-like molecules with desired characteristics of intact antibodies. This BsAb can act as PK-modulated receptor antagonist. It is designed for the research of Lupus, rheumatoid arthritis therapy.

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Specifications

Targets

albumin & IL-6R

Type

scFv-based Bispecific Fragments

Species Reactivity

Human

Application

FuncS; Promising therapeutic agent

Related Disease

Systemic lupus erythematosus (SLE); Rheumatoid arthritis (RA)

Targets

Target 1

albumin

Gene ID

213

UniProt ID

P02768

Alternative Names

ALB; albumin; HAS; PRO0883; PRO0903; PRO1341

Target 2

IL-6R

Gene ID

3570

UniProt ID

P08887

Alternative Names

IL6R; IL-6R; interleukin 6 receptor; IL6Q; gp80; CD126; IL6RA; IL6RQ; IL-6RA; IL-6R-1

Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

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Recombinant Human Anti-albumin x Human Anti-IL-6R Bispecific Antibody (scFv-Fc) (CAT#: BSCFV-H194)

Specifications

Targets

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