Recombinant Human Anti-albumin x Human Anti-IL-6R Bispecific Antibody (scFv-Fc-scFv) (BSTF-H194)

Recombinant Anti-albumin x Anti-IL-6R Bispecific Antibody (scFv-Fc-scFv) is designed to be expressed as one chain, then assembled to a homodimer of bivalent scFv fragments and the Fc region of IgG. The anti-albumin scFv is fused to the N-terminus of Fc via a hinge region while another anti-IL-6R scFv is linked to the C-terminus of Fc. This scFv-Fc-scFv format has 2+2 antigen-binding valency by employing different scFv fragments. This BsAb can act as PK-modulated receptor antagonist. It is designed for the research of Lupus, rheumatoid arthritis therapy.

Datasheet INQUIRY

Specifications

Targets

albumin & IL-6R

Type

scFv-based Bispecific Fragments

Species Reactivity

Human

Application

FuncS; Promising therapeutic agent

Related Disease

Systemic lupus erythematosus (SLE); Rheumatoid arthritis (RA)

Targets

Target 1

albumin

Gene ID

213

UniProt ID

P02768

Alternative Names

ALB; albumin; HAS; PRO0883; PRO0903; PRO1341

Target 2

IL-6R

Gene ID

3570

UniProt ID

P08887

Alternative Names

IL6R; IL-6R; interleukin 6 receptor; IL6Q; gp80; CD126; IL6RA; IL6RQ; IL-6RA; IL-6R-1

Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

Online Inquiry

Customer Reviews and Q&As

There are currently no customer reviews or questions for Recombinant Human Anti-albumin x Human Anti-IL-6R Bispecific Antibody (scFv-Fc-scFv) (BSTF-H194). Click the button below to contact us or submit your feedback about this product.

Recombinant Human Anti-albumin x Human Anti-IL-6R Bispecific Antibody (scFv-Fc-scFv) (CAT#: BSTF-H194)

Specifications

Targets

Customer Reviews and Q&As